Cohort Study

SHARC Cohort Study

The Shiraz HIV Cohort Study (SHCS)

The Shiraz HIV Cohort Study is a collaboration that started in 2012 to put together data relating to clinical care,treatment and counseling of HIV.

The SHCS is prospective and retrospective study. The SHCShas a multidisciplinary approach (epidemiology,social science, virology, immunology and clinical medicine). This expertise is contributed directly to advances in prevention,diagnosis and management of HIV infection. The initial aim of the SHCS is to investigate the prevalence,incidence and risk factors of HIV-1 infection and AIDS, the natural history and pathogenesis of HIV-1 infection, and the effects of interventions. Also, psychosocial scientific studies concentrating on understanding behavioral trends and determinants of sexual behavior are done,as well as studies on the clinical course of HIV infection.
The study organization consists of a steering committee and a coordinating group,and the research themes are managed by sub-study groups. Members of the committee,sub-groups and other collaborators include virologists, infectious disease specialist, immunologist, pharmacologist, psychologist, statisticians and epidemiologists with expertise in infectious disease surveillance.
The study database contains routinely collected clinical information on HIV positive individuals. The study design is based on annual data collection,data cleaning and data merging processes,leading to the preparation of an annual dataset. When finished,the dataset is then used for data analyses,leading to peer-reviewed publications and other
study outputs. Missing and inconsistent data is investigated and the datasets audit. Records identified as relating to the same patient is merged,and cross-checks made with Shiraz death registers to improve the accuracy of death reporting.

Our team members (Principle investigators):
- Dr Abbas Rezaeian Zadeh (epidemiologist)
- Dr Nasrin Motazedian (Social Medicine)
- Dr Hassan Joulaei (Pharmacologist)
- Dr. Shohreh Beheshti (Infectious Disease)
- Dr. Mohammad Ali Davarpanah (Infectious Disease)
- Mahmood Amini Lari (Psychologist)
- Dr. Parvin Afsar Kazerooni (Social Medicine)
- Dr. Mohsen Moghadami (Infectious Disease)
- Dr. Mohammad Motamedifar (Virologist)
- Dr. Foroogh Nejatollahi (Immunologist)
-Nooshin Zarei (Demoghraph